Please site this table as follows:
Eekers D, Lambrecht M, Nyström PDW, Swinnen A, Wesseling FWR, Roelofs E, Troost EG EPTN consensus-based guideline for the tolerance dose per fraction of organs at risk in the brain CancerData, 2018; doi:10.17195/candat.2018.01.1
EPTN consensus-based guideline for the tolerance dose per fraction of organs at risk in the brain
In collaboration with the European Particle Therapy Network, a consensus table of tolerance doses for Organs at Risk in the brain was created. These values were all defined as a near maximum EQD2 values. Using the linear quadratic formula the doses are recalculated depending on the number of fractions.
EQD2 = equivalent dose in 2Gy-fractions
D = the total dose
d = the dose per fraction
α/β = were derived from literature
Please note that this table does not include Dmean dose constraints, since these are comprised of the treatment plan's mean dose and standard deviation, which are patient- and technique-dependent (for further reading and conversion [1,2]).
(NB Downloads are below)
References:
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